Thrombus

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Aortic tissue valves: aspirin or warfarin?
Thrombus, Volume 9, Number 3.

Following the first mechanical heart valve replacements more than 40 years ago, unacceptably high rates of arterial thromboembolic complications were soon reported. This led to the routine use of anticoagulant prophylaxis with inhibitors of vitamin K-dependent clotting for long-term prophylaxis in patients receiving mechanical heart valves.

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