Thrombus

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Calciphylaxis: rarely seen and poorly understood
Thrombus, Volume 11, Number 4.

Calciphylaxis, also referred to as calcific uraemic arteriolopathy, is a rare calcification syndrome associated with cutaneous ischaemic necrosis. It is seen almost exclusively in patients with renal disease and secondary hyperparathyroidism but can, rarely, occur in their absence. Its incidence is rising. It is often diagnosed late, contributing to the very high mortality rate, ranging between 50%–80% of cases. Death in these patients is often attributed to associated wound infection, sepsis and organ failure.

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