Thrombus

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Oral anticoagulation for atrial fibrillation
Thrombus, Volume 12, Number 4.

The benefit in symptomatic atrial fibrillation (AF) of oral anticoagulant therapy is well established in clinical trials. Overall, stroke is five to six times more prevalent in patients with AF, with a 1% risk per year for patients over 65 years with no risk factors, rising to 12% per year for patients over 65 years with previous stroke, transient ischaemic attack (TIA) or venous thromboembolic disease. Furthermore, stroke in AF patients is associated with a greater mortality, morbidity, disability and longer inpatient admissions.

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