Thrombus

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Assessing dabigatran for atrial fibrillation
Thrombus, Volume 13, Number 3.

The latest treatment to emerge in the struggle to find new and safe anticoagulant treatments is dabigatran, a direct thrombin inhibitor currently licensed in the UK for thromboprophylaxis following hip and knee surgery, as detailed in this issue. Since ximelagatran sank without trace following adverse liver events highlighted with prolonged administration, long-term safety issues remain a priority for agents in development.

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